The Chilkoti group carries out research in two areas: (1) Biomolecular Materials, with a focus on genetically encoded stimulus responsive peptide polymers and fusion proteins for application in protein purification and drug delivery; and (2) Biointerface Science, with a focus on protein-polymer conjugates, the development of low-cost, point-of-care clinical diagnostics, and plasmonic biosensors.
Chilkoti Group
Recent Publications
“Programmable synthetic biomolecular condensates for cellular control”, Nature Chemical Biology, 2023.
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“Polyethylene Glycol‐Like Brush Polymer Conjugate of a Protein Drug Does Not Induce an Antipolymer Immune Response and Has Enhanced Pharmacokinetics than Its Polyethylene Glycol Counterpart”, Advanced Science, vol. 9, no. 11, p. 2103672, 2022.
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“Brachytherapy via a depot of biopolymer-bound 131I synergizes with nanoparticle paclitaxel in therapy-resistant pancreatic tumours”, Nature Biomedical Engineering, vol. 6, no. 10, pp. 1148 - 1166, 2022.
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