Chilkoti Group
The Chilkoti group carries out research in two areas: (1) Biomolecular Materials, with a focus on genetically encoded stimulus responsive peptide polymers and fusion proteins for application in protein purification and drug delivery; and (2) Biointerface Science, with a focus on protein-polymer conjugates, the development of low-cost, point-of-care clinical diagnostics, and plasmonic biosensors.
Recent Publications
Calcium binding peptide motifs from calmodulin confer divalent ion selectivity to elastin-like polypeptides. Biomacromolecules (2013): ASAP. Abstract
Predicting Transition Temperatures of Elastin-Like Polypeptide Fusion Proteins. Biomacromolecules. 14.5 (2013): 1514-1519. Abstract
Three-in-One Chromatography-Free Purification, Tag Removal, and Site-Specific Modification of Recombinant Fusion Proteins Using Sortase A and Elastin-like Polypeptides. Angewandte Chemie International Edition. 52.13 (2013): 3703-3708. Abstract
Injectable protease-operated depots of glucagon-like peptide-1 provide extended and tunable glucose control. Proceedings of the National Academy of Sciences. 110.8 (2013): 2792-2797. Abstract
Self-Assembly of Thermally Responsive Nanoparticles of a Genetically Encoded Peptide Polymer by Drug Conjugation. Angewandte Chemie International Edition. 52.6 (2013): 1683-1687.
Direct Fluorescence Detection of RNA on Microarrays by Surface-Initiated Enzymatic Polymerization. Analytical Chemistry. 85.1 (2013): 426-433. Abstract
Recent News
May 21, 2013:
Well, it's official now; Vina and Felipe are finally allowed to don the hoods of their (Jedi) cloaks! Click to see a few photos from their Ph.D. Hooding Ceremony.
May 7, 2013:
Chilkoti Group racked up major awards at the Duke BME PhD student retreat: (1) Congratulations to Sarah for winning consolation prize for Best 1-Minute Pitch with her poem entitled "Extrinsically controlled intracellular drug delivery". Please click here for the full text of this literary wonder. (2) Stacey won 3rd Best Poster Prize with the magic poster that has nabbed her 2 awards in the last month. With its winning career over, it will now officially be retired and hung on our wall of fame (see the hallway outside of CIEMAS 3325). (3) And Jonathan won the Big Kahuna-- Best Talk at the BME retreat.
April 26, 2013:
Let them have cake: Chilkoti group thanks its graduating seniors 
for their contributions to the lab and congratulates them on graduating.
